“Synthesis of a DNA-encoded chemical library”
In this Master thesis project, you will play a pivotal role in the design, synthesis and analysis of a DNA-encoded chemical library. You will be responsible for creating a novel library and ensuring the successful establishment of the synthesis process. The project involves a combination of synthetic chemistry, library design and analytical work with LC-MS, making it an exciting and challenging project for candidates passionate about advancing drug discovery.
- Develop and optimize synthetic protocols, ensuring high-quality library production
- Execute chemical reactions to synthesize a diverse DNA-encoded chemical library
- Perform analytical analysis of synthesized compounds (HPLC, LC-MS)
- Maintain accurate records of experimental procedures, data, and results
- Troubleshoot and resolve synthetic and analytical challenges as they arise
- Contribute to the development of new methodologies and techniques in library synthesis
- Bachelor’s degree in Chemistry or a related field with strong background in chemistry (e. g. Biochemistry, Pharmacy, Biological Medicine, etc.)
- Self-motivated with a strong commitment to achieving project goals
- Strong problem-solving skills and attention to detail
Please also check out dynabind.com for more details about our pipelines.